Samuel Alabaster (Robert Pattinson), an affluent pioneer, ventures across the American Frontier to marry the love of his life, Penelope (Mia Wasikowska). As Samuel traverses the Wild West with a drunkard named Parson Henry (David Zellner) and a miniature horse called Butterscotch, their once-simple journey grows treacherous, blurring the lines between hero, villain and damsel. A loving reinvention of the western genre from the Zellner brothers (Kumiko, the Treasure Hunter), Damsel showcases their trademark unpredictability, off-kilter sense of humor, and unique brand of humanism.